Àireamh Cas Glybenclamide: 10238-21-8 Foirmle Molecular: C23H28ClN3O5S

Tuairisgeul goirid:

Àireamh Cas: 10238-21-8

Ainm Ceimigeach: Glybenclamid

Foirmle Molecular:C23H28ClN3O5S

Cuir post-d thugainn

Mion-fhiosrachadh toraidh

Bathar Tags

Co-fhaclan

5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]Amino]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]Amino]SULphonail]Phenyl]ETHYL]-2-METHOXYBENZAMIDE
5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE
GIBENCLAMIDE
GLIBECLAMIDE
GLYBENCLAMIDE
GLYBENZCYCLAMIDE
GLYBURIDE
LABOTEST-BB LT00244861
MIONNACHADH
NP-[2-(5-CHLORO-2-METHOXYBENZAMIDO)ETHYL]BENZENESULFONYL-N'-CYCLOHEXYLUREA
1-((p-(2-(Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl urea
1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl-ure
1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea)
1-[[p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea
1-[[p-[2-(chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexyl-Urea
5-chloro-n-(2-(4-(((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2
Abbenclamid
adiab

Sònrachadh Bathar

Rubha leaghaidh	173-175 ° C
Dùmhlachd	1.1805 (tuairmse garbh)
teòthachd stòraidh	Àile neo-sheasmhach, teòthachd an t-seòmair 2-8 ° C
so-thuigsinn	ethanol: soluble2mg/mL
gnìomhachd optigeach	Chan eil
Coltas	Pùdar Criosta Geal
Purity	≥98%

Tuairisgeul

Tha Glyburide (10238-21-8) na àidseant hypoglycemic beòil an dàrna ginealach.Achdan tro sheanail K+ a tha an urra ri ATP (Kir6, KATP) block.1? A’ bacadh sruthan Kir6 anns a’ pancreas, ag adhbhrachadh àrdachadh ann an Ca2+ intracellular agus secretion insulin.Bidh Glyburide cuideachd a’ cur bacadh air seanalan Cl-CFTR ath-chuingealaichte le IC50 de 20 μM.2?Cell permeable.